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Laboratory of Yohan Bossé 

Genomics of Heart & Lung Diseases

Cardiovascular diseases
 

  • Calcific aortic valve stenosis

  • Bicuspid aortic valve

Respiratory diseases
 

  • Lung cancer

  • COPD

  • Asthma

  • Alpha-1 antitrypsin deficiency

Biobanking
 

  • Human DNA

  • Lung tissues

  • Valve tissues

Genomic approaches
 

  • Genome-Wide Association Study (GWAS)

  • Candidate gene study

  • eQTL mapping study

  • Transcriptome-Wide Association Study (TWAS) 

Genomic technologies
 

  • DNA genotyping and sequencing

  • RNA-Sequencing

  • Single-cell RNA-sequencing

  • Genome-wide gene expression microarrays

  • Genome-wide expression of microRNA and methylation marks

Genomic Analysis
 

  • Bioinformatics

  • Programming and statistical genetic analyses

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